Clinical History

The patient is a 67 year old male with known prostate cancer. The prostate was removed in 1993. His PSA levels have been doubling approximately every nine months and his PSA is now 13.2. We have been asked to examine him for the presence of prostate carcinoma in the prostate bed as well as look for prostatic pelvic metastases.

Technique

On 3/14/97 the patient received an intravenous injection of 5.3 millicuries of Indium 111 Prostascint. Twenty minutes later SPECT imaging of the pelvis was carried out. The study is technically satisfactory. Reconstruction was performed according to current specifications. Great vessels, marrow uptake and bladder are identified for comparison with later studies.

Findings

On 3/18/97 (day 4) a whole body Prostascint scan was performed. Anterior and posterior whole body images were obtained. A normal distribution of the Indium 111 label is identified in liver, heart blood pool, genitalia and spleen. SPECT imaging of the pelvis was then carried out. There was no patient motion. Images were reconstructed in standard fashion. Transverse, coronal, sagittal images were obtained. Penile activity is identified in transverse images. Comparison with the day 0 blood pool images suggests there is an increased radiotracer localization in the prostate bed just superior to the base of the penis and posterior and inferior to the bladder. Repeat SPECT imaging with static anterior posterior planar imaging was performed at day 6. Again noted in the prostate bed is a focal increase in activity suggesting active disease. In transverse images 26 and 27 in the floor of the pelvis to the left of the prostate bed is an asymmetrical region of focal uptake suggestive of lymph node metastasis.

Impressions

PROBABLE ACTIVE PROSTATIC CANCER IN THE PROSTATE BED WITH PROBABLE LEFT PELVIC LYMPH NODE METASTASIS.

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