Clinical History

This is a 51-year-old female with poor memory, visual tracking, dementia, and myoclonic jerking. No prior studies are available for comparison.

Technique

Under conditions of ambient light and sound in the Division of Nuclear Medicine, the patient received an intravenous injection of 9.24 mCi of F-18 FDG and 45 minutes later, PET imaging of the brain was carried out. Images were reconstructed in the transverse, coronal, sagittal, and volume displays.

Findings

There is diminished F-18 FDG uptake in the parietal lobes bilaterally as well as the medial temporal and anterior temporal regions bilaterally. There is normal FDG uptake in the frontal and occipital lobes bilaterally. There is also normal FDG uptake along the basal ganglia and thalami.

Impressions

DIMINISHED FDG UPTAKE IN THE PARIETAL LOBES AS WELL AS THE ANTERIOR TEMPORAL AND MEDIAL TEMPORAL REGIONS WHICH ARE COMPATIBLE WITH ALZHEIMER'S DISEASE.

Comments

The patients MRI scan showed two small punctate foci of increased signal in the right centrum semiovale/corona radiata, which may represent some very early changes of small vessel disease. Otherwise normal MRI of the head.